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Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
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Episodes
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- E1 AcceptanceSep 13, 2005 · 44 min · ★ 7.6
Synopsis
When a Death Row inmate mysteriously and suddenly collapses after hallucinating, House jumps at the chance to take the case for its difficulty and because it's "cool."
Guest stars: LL Cool J (Clarence), Marshall Bell (Warden), Bryce Johnson (James), Mustafa Shakir (D'Vontray), Christie Lynn Smith (Cindy), Mike G. (Carlos), Tony Ross (Emmitt), Anesha Ndiaye (Darriene)
- E2 AutopsySep 20, 2005 · 44 min · ★ 8.2
Synopsis
A girl's unimaginable bravery toward her terminal illness makes House suspicious as he puts a life-or-death decision about her case in her young hands.
Guest stars: Jewel Christian (Pam), Sasha Pieterse (Andie), Randall Park (Brad), William Jones (Dr. Murphy), Gwen Holloway (Neurosurgeon), Eamon Hunt (Neurosurgeon), Jonathan Fraser (Salesperson), Hira Ambrosino (Dr. Chen, Anesthesiologist)
- E3 Humpty DumptySep 27, 2005 · 44 min · ★ 7.6
Synopsis
Cuddy struggles with a case of guilt when her handyman is injured while at her place, and House and his team have to work fast to save the young man's pursuit of the American Dream.
Guest stars: Ignacio Serricchio (Alfredo), Christine Avila (Luisa), Charles Robinson (Robert), J.R. Villarreal (Manny), Sela Ward (Stacy Warner)
- E4 TB or Not TBNov 1, 2005 · 44 min · ★ 7.3
Synopsis
House's patient is willing to die in order to further his social cause.
Guest stars: Mary Wickliffe (Mandy), Hansford Prince (Bogale), Harry F. Brockington IV (Dahoma), Joram Moreka (Father), Ron Livingston (Dr. Sebastian Charles), Andrea Bendewald (Cecilia Carter), Ken Weiler (Jerry)
- E5 Daddy's BoyNov 8, 2005 · 44 min · ★ 7.5
Synopsis
Lies between a father and son may prevent House and his team from saving their patient.
Guest stars: Mackenzie English (Katrina), Brian D. Johnson (Taddy's Boss), Jon Hershfield (Timekeeper), Brian Chase (EMT), Diane Baker (Blythe House), Mark DeLisle (Paramedic), Bobbin Bergstrom (Nurse), Matt McKenzie (Dr. Fedler)
- E6 SpinNov 15, 2005 · 44 min · ★ 7.5
Synopsis
House's wheels start turning when a pro-cyclist admits to taking performance-enhancing drugs.
Guest stars: Currie Graham (Mark Warner), Nathan Kress (Scott), Kristoffer Polaha (Jeff Forrester), Taraji P. Henson (Moira), Tom Lenk (Allen), Alanna Ubach (Dr. Louise Harper), Austin Whitlock (Matthew), Scott Kradolfer (Matthew's Father)
- E7 HuntingNov 22, 2005 · 44 min · ★ 7.6
Synopsis
A patient with AIDS stalks House to get him to take his case; House and Stacy stalk a mouse in her attic; and Cameron faces a health scare of her own.
Guest stars: Currie Graham (Mark Warner), Wings Hauser (Michael Ryan), Matthew John Armstrong (Kalvin Ryan), Hamilton Mitchell (Infection Control Officer), Sela Ward (Stacy Warner)
- E8 The MistakeNov 29, 2005 · 44 min · ★ 7.7
Synopsis
A patient's death prompts an investigation into whether Chase or House may have been responsible for her death.
Guest stars: Ryan Hurst (Sam McGinley), Allison Smith (Kayla McGinley), John Rubinstein (Dr. Ayersman), Sterling Beaumon (Boy Magician), Sammi Hanratty (Dory), Adair Tishler (Nikki), John Lafayette (Dr. Schisgal), Greg Winter (Chuck)
- E9 DeceptionDec 13, 2005 · 44 min · ★ 7.7
Synopsis
With Foreman as House's supervisor, the team must figure out if a woman who cried wolf too many times is really ill.
Guest stars: Cynthia Nixon (Anica Javanovich), Peter Abbay (Cab Driver), Nell Rutledge (Hailey), Rod Britt (Teller), Larry Weissman (Fat Man), David DeSantos (ER Doctor), Patrick LoSasso (Do-Gooder), Xhercis Mendez (Imelda)
- E10 Failure to CommunicateJan 10, 2006 · 44 min · ★ 7.6
Synopsis
A journalist's head injury results in unintelligible speech, leaving House and his team at a loss; and the heat is turned up between House and Stacy when they're out of town.
Guest stars: Michael Len (9 Year Old Boy), Sela Ward (Stacy Warner), Michael O'Keefe (Fletcher Stone), Mimi Kennedy (Greta), Erica Gimpel (Elizabeth Stone), Bruce French (Peter Foster), Pat Caldwell (Mary Jean), Amy Margolis (Mother)
- E11 Need to KnowFeb 7, 2006 · 44 min · ★ 7.1
Synopsis
While House's staff tries to diagnose a woman whose uncontrollable muscle flailing caused her to crash her car, House and Stacy try to resolve their relationship issues once and for all. Cameron refuses to take her HIV test, wary of the results.
Guest stars: Julie Warner (Margo Dalton), Currie Graham (Mark Warner), Edward Kerr (Ted Dalton), Elle Fanning (Stella Dalton), Sela Ward (Stacy Warner), Holly Daniels (Debbie)
- E12 DistractionsFeb 14, 2006 · 44 min · ★ 7.8
Synopsis
While a severely burned teenager is admitted and his blood tests come back with strange results, House makes himself the guinea pig in his own unofficial tests of a new drug designed to treat migraines to prove a former medical school colleague is wrong about the drug.
Guest stars: Lisa Darr (Emily), Christopher Cousins (Doug), Dan Butler (Dr. Philip Weber), Michael Merton (Anesthesiologist), James Immekus (Adam), Dorothea Harahan (EMT), Judy Louise Johnson (Surgeon), Kristen Pate (Paula)
- E13 Skin DeepFeb 20, 2006 · 44 min · ★ 7.7
Synopsis
House uncovers a startling secret when he treats a teenage supermodel for heroin addiction. Meanwhile, Wilson hopes the increased leg pain in House's leg is an indication his leg nerves are regenerating.
Guest stars: Tom Verica (Martin Robinson), Cameron Richardson (Alexandra Robinson), James DuMont (George), Jim Hoffmaster (Surgeon), Karis Campbell (Pregnant Woman), Donzaleigh Abernathy (Brady), John Burke (Austin), Stephanie Venditto (Nurse Brenda Previn)
- E14 Sex KillsMar 7, 2006 · 44 min · ★ 7.6
Synopsis
House takes the case of a man who experienced a seizure but wasn't aware it happened. When the man suffers a heart attack and needs a heart transplant, the team races to diagnose a dead woman's illness so they can harvest her heart to save their living patient.
Guest stars: Greg Grunberg (Ronald Neuberger), Howard Hesseman (Henry Errington), Adam Busch (Tony), Keri Lynn Pratt (Amy Errington), Yvette Nicole Brown (Ellen Stambler), Stephen DeCordova (Chief Surgeon #2), Jean St. James (Cecile), Noel Conlon (First Table East)
- E15 CluelessMar 28, 2006 · 44 min · ★ 7.7
Synopsis
House believes a woman is trying to kill her husband and tries to find the proof to confirm his suspicions. When Wilson moves in with House after separating from his wife, he learns Wilson is a great cook.
Guest stars: Eddie Mills (Bob Prodeman), Samantha Mathis (Maria Prodeman), Peter Birkenhead (Vincent Lambert), Stephanie Erb (Charlotte Lambert), Yareli Arizmendi (Lady)
- E16 SafeApr 4, 2006 · 43 min · ★ 8.0
Synopsis
A teenage heart transplant patient is rushed to the hospital when she has an allergic reaction while living in a "clean" room, and House and Wilson work out the kinks of their new living arrangement.
Guest stars: Michelle Trachtenberg (Melinda Bardach), Jake McDorman (Dan), Mel Harris (Barbara Bardach), Lance Guest (Lewis Bardach)
- E17 All InApr 11, 2006 · 44 min · ★ 8.1
Synopsis
When a six-year-old boy is brought in with the same symptoms as another patient who died years ago under House's care, House believes the cases are identical and he can predict the course of the boy's illness. Meanwhile, the clinic hosts a poker night to benefit the oncology department.
Guest stars: Laura Allen (Sarah Alston), Mackenzie Astin (Alan Alston), Carter Page (Ian Alston), Michelle Harrison (Nicole Ballard), Daylon Reese (Child), Al Espinosa (Dr. Wells), Purva Bedi (Teacher)
- E18 Sleeping Dogs LieApr 18, 2006 · 44 min · ★ 7.4
Synopsis
House has to work fast when a woman comes in with a life-threatening case of insomnia. Meanwhile Cameron is angry at Foreman for stealing an article she worked on.
Guest stars: Dahlia Salem (Max), Alice Lo (Mrs. Ling), K.T. Thangavelu (Surgeon), Kendall Clement (Anesthesiologist), Jayma Mays (Hannah), Julia Ling (Anne)
- E19 House vs. GodApr 25, 2006 · 44 min · ★ 7.8
Synopsis
House treats a 15 year old faith healer, while Wilson feels left out when he finds out House has a weekly poker game.
Guest stars: Sandra Marshall (Agnes), Michael Edwin (Tax Accountant), Marco Martinez (Dry Cleaner), David Cheaney (Bus Stop), Thomas Dekker (Boyd), William Katt (Walter), Tamara Braun (Grace Palmieri)
- E20 Euphoria (1)May 2, 2006 · 44 min · ★ 8.4
Synopsis
When a police officer with a gunshot wound to the head and uncontrollable laughter is admitted, House and the team are baffled. When Foreman begins showing the same symptoms, they race to determine the cause of the illness before Foreman's condition takes the same path.
Guest stars: Scott Michael Campbell (Officer Joe Luria), Loreni Delgado (Officer Haines), Chioke Dmachi (Baby Shoes), Calvin King (Transvestite), Chil Kong (Morgue Tech), Guy Nardulli (Coughing Cop)
- E21 Euphoria (2)May 3, 2006 · 44 min · ★ 8.4
Synopsis
Foreman continues to experience the same progression of symptoms as the police officer. When he realizes he may be facing imminent death, he calls his father who comes to his son's side. As it comes down to a race against time, House believes the solution to the illness is in the police officer's apartment.
Guest stars: Scott Michael Campbell (Officer Joe Luria), Charles S. Dutton (Rodney Foreman), Leigh-Allyn Baker (Claire)
- E22 ForeverMay 9, 2006 · 44 min · ★ 7.5
Synopsis
A young mother has a seizure while bathing her newborn son and nearly drowns him. House and the team have two cases at one time as they try to save the infant and determine the cause of the mother's seizures.
Guest stars: Toni Lewis (NICU Nurse), Kevin Moon (EMT), Hillary Tuck (Kara Mason), Kip Pardue (Brent Mason)
- E23 Who's Your Daddy?May 16, 2006 · 44 min · ★ 7.4
Synopsis
A 16-year-old Hurricane Katrina victim suffering from hallucinations as a result of the tragedy is brought to House by his former bandmate who recently found out the girl is his daughter. Although House fears his friend is being scammed, he takes the case. As he works his way through the girl's lies so he can diagnose and treat her, he's forced to tell a few lies of his own.
Guest stars: America Olivo (Ingrid), Owen Pearce (Max), Tuffet Schmelzle (Young Mother), Krista Lewis (Flight Attendant), Aasha Davis (Leona), D. B. Sweeney (Dylan Crandall)
- E24 No ReasonMay 23, 2006 · 44 min · ★ 8.6
Synopsis
House is shot by a former patient and must share a recovery room with the gunman.
Guest stars: Michelle Clunie (Judy), Elias Koteas (Jack Moriarty), Chris Tallman (Vince), Obie Sims (Cuddy's Patient), Bobbin Bergstrom (Nurse)
Cast & crew
Created by David Shore
Hugh Laurie
Robert Sean Leonard
Omar Epps
Jesse Spencer
Odette Annable
Peter Jacobson
Lo MutucVideos
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Behind the scenes
Featurettes
Images · 14
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Reviews · from TMDB members
Ibraheem...Oct 29, 2017
I liked this show because House's character, but I was oblivious to most of their medical conversations. An advice: Don't watch it unless you understand a lot of medical terminology.
RobMay 10, 2023
Hugh Laurie brings the house down in this role. sorry, I just had to make that pun. If you want to be utterly entertained by a self-destructive Vicodin addict as he childishly plays God with the lives of his patients and root for him every step of the way as he does it, then this is the series for you.
gishkyDec 18, 2025
"This dying child needs more ratbites!" - Doctor House, probably - while popping another bottle of vicodin
