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Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
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Episodes
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- E1 PilotNext upNov 16, 2004 · 44 min · ★ 7.8
Synopsis

Dr. Gregory House, a brilliant diagnostician but devoid of bedside manner, and his elite team of young medical experts rush to save the life of a kindergarten teacher who started speaking gibberish and passed out in front of her class.
Guest stars: Robin Tunney (Rebecca Adler), Andrew Airlie (Orange Colored Patient), Rekha Sharma (Melanie Landon), Ava Hughes (Sydney), Ethan Kyle Gross (Molnar), Janet Glassford (Reception Nurse), Candus Churchill (Substitute Teacher), Maya Massar (Asthma Mom)
- E2 PaternityNov 23, 2004 · 43 min · ★ 7.6
Synopsis

Dr. House goes with his gut and performs an unethical act to prove what he suspects to be the link to a teenage lacrosse player's illness in order to save the boy's life.
Guest stars: Scott Mechlowicz (Dan), Robin Thomas (Dan's Father), Wendy Gazelle (Dan's Mother), Alex Skuby (John Funsten), Scott Hochstadt (Jake), Paul Ganus (Trainer), Kylee Cochran (Young Woman)
- E3 Occam's RazorNov 30, 2004 · 44 min · ★ 7.3
Synopsis

Dr. House and his team race to save a young man who may have not one, but two illnesses killing him.
Guest stars: Kevin Zegers (Brandon Merrell), Alexis Thorpe (Mindy), Faith Prince (Becky Merrell), Lauren Cohn (Jodi Matthews), Jason Stuart (Adam Brown), John Kelly (Robert Merrell), Beth Hall (Shelly Lever), Ben Campbell (Jerry Morris)
- E4 MaternityDec 7, 2004 · 43 min · ★ 7.6
Synopsis

A maternity ward epidemic forces House to decide whether to save the life of one child over another.
Guest stars: Ever Carradine (Karen Hartig), Hedy Burress (Jill), Sam Trammell (Ethan Hartig), Kenneth Choi (Dr. Lim), Benjamin John Parrillo (Dr. Kubisak), Cress Williams (Hospital Attorney), Melissa Marsala (Judy Lupino), Alexandra Bokyun Chun (Kim Chen)
- E5 Damned If You DoDec 14, 2004 · 44 min · ★ 7.5
Synopsis

Dr. House's approach is questioned when he treats a nun for what he believes to be an allergy, not realizing the nun's past is coming back to haunt her.
Guest stars: Dakin Matthews (Marvin), Peter James (Priest), Taji Coleman (Tech), Elizabeth Mitchell (Sister Mary Augustine), Lori Rom (Sister Mary Pius), Lucinda Jenney (Sister Mary Eucharist), Ann Dowd (Mother Superior)
- E6 The Socratic MethodDec 21, 2004 · 44 min · ★ 7.8
Synopsis

The case of a schizophrenic mom with a deadly disease and her teenage son who have traded caretaking roles holds a special interest for Dr. House.
Guest stars: Aaron Himelstein (Luke Palermo), Stacy Edwards (Lucy Palermo), John Prosky (Dr. Bergin), Pat Musick (Trina Wyatt), Sonya Eddy (Sally), Lilas Lane (Terri), David Vegh (Clark), Veronica Leigh (Wendy)
- E7 FidelityDec 28, 2004 · 44 min · ★ 7.4
Synopsis

Dr. House's diagnosis of a married woman with a rare sleep disorder forces her and her husband to examine their marriage and question their trust for each other.
Guest stars: Dominic Purcell (Ed Snow), Myndy Crist (Elyse Snow), Brennan Elliott (Adam), Clementine Ford (Samantha "Sam" Campbell), Henri Lubatti (Master Chef Jacques), Endre Hules (Sous Chef)
- E8 PoisonJan 25, 2005 · 44 min · ★ 7.3
Synopsis

House and his team have to act fast when a high school student is admitted with a mysterious and lethal poisoning, especially when they discover more teens have been diagnosed with the same deadly illness.
Guest stars: Roxanne Hart (Margo Davis), John Patrick Amedori (Matt Davis), Kurt Fuller (Mark Adams), Andy Milder (Bus Driver), McNally Sagal (Mrs. Miller), Shirley Knight (Georgia Adams), Jim Lau (Chou-Young Ling), Linda Wang (Jen Ling)
- E9 DNRFeb 1, 2005 · 44 min · ★ 8.0
Synopsis

House has to defend himself when he treats a patient who has legally chosen to refuse treatment.
Guest stars: Harry Lennix (John Henry Giles), Chloe Webb (Cora), Mike Starr (Willie), Victor Raider-Wexler (Judge Winter), Rif Hutton (Morris), Michael Oberlander (Ross), David Conrad (Dr. Marty Hamilton), Brandy Norwood (Brandy)
- E10 HistoriesFeb 8, 2005 · 44 min · ★ 7.8
Synopsis

Dr. House and the team treat a homeless woman whose worsening symptoms and unknown identity prove to be a complex mystery.
Guest stars: Leslie Hope (Victoria Madsen), Larry Clarke (Officer Gilmar), Smith Cho (Julia), Ogy Durham (Chris Dewey), Leslie Karpman (Jodi), Charles C. Stevenson Jr. (Walter), Suzanne Ford (Mrs. Whitney), Brandon Brocato (Phil)
- E11 DetoxFeb 15, 2005 · 44 min · ★ 8.1
Synopsis

Dr. House takes Cuddy's challenge to go off his painkillers for a week, but the effects of his withdrawal symptoms may put his patient in danger.
Guest stars: Mark Harelik (Mr. Foster), Nicholas D'Agosto (Keith Foster), Amanda Seyfried (Pam), Akiko Morison (Anesthesiologist), America Olivo (Ingrid), Maurice Godin (Dr. Hourani), Marco Pelaez (Hospital Pharmacist)
- E12 Sports MedicineFeb 22, 2005 · 43 min · ★ 7.6
Synopsis

A baseball player's comeback is cut short when he breaks his arm and House and his team have to act fast to figure out what is causing major bone loss that's killing the player and his dreams.
Guest stars: Scott Foley (Hank Wiggen), Meredith Monroe (Lola), Art LaFleur (Warner Fitch), Salli Richardson-Whitfield (Sharon), Bryan Singer (Bryan Singer), Deirdre M. Smith (Carol Moffatt), Richard Swaidan (College Student), Sean Everett (Patient)
- E13 CursedMar 1, 2005 · 44 min · ★ 7.5
Synopsis

Dr. House's young patient believes his illness is the result of a curse while House uncovers important information about Chase's father.
Guest stars: Nestor Carbonell (Jeffrey Reilich), Tracy Middendorf (Sarah Reilich), David Henrie (Tommy), Daryl Sabara (Gabriel "Gabe" Reilich), Patrick Bauchau (Dr. Rowan Case), Dennis Bendersky (Davey), R.J. Root (Sam), Jack Walsh (Ozzy)
- E14 ControlMar 15, 2005 · 44 min · ★ 7.9
Synopsis

The hospital's new Chairman of the Board has it out for Dr. House, questioning his importance to the hospital and threatening to eliminate House and his team.
Guest stars: Sarah Clarke (Carly Forlano), Sunny Mabrey (Jenny), Vivian Bang (Robin), Andrew Borba (Mr. van der Meer), Chi McBride (Edward Vogler), Dar Dixon (Don), Joshua Miller (Ricky), David Joyner (Cardiac Surgeon)
- E15 Mob RulesMar 22, 2005 · 44 min · ★ 7.3
Synopsis

Dr. House and his team race to diagnose a member of the mob and get him well enough to testify and enter the witness protection program while Cuddy works to convince Vogler of House's importance to the hospital.
Guest stars: Danny Nucci (Bill Arnello), Joseph Lyle Taylor (Joey Arnello), David Burke (Everhardt), Chi McBride (Edward Vogler), A.J. Trauth (Henry), Greg Collins (Marshal Brady), Ingrid Sanai Buron (Kimberly)
- E16 HeavyMar 29, 2005 · 44 min · ★ 7.9
Synopsis

Dr. House and his team try to uncover the reason a 10-year-old has a heart attack while House suspects one of his team is selling him out to Vogler.
Guest stars: Jennifer Stone (Jessica Simms), Cynthia Ettinger (Mrs. Simms), Ramón Franco (Mr. Hernandez), Karen Goberman (Mrs. Ayers), Chi McBride (Edward Vogler), Susan Slome (Lucile Hernandez), Teddy Lane Jr. (Mr. Conroy), Alyson Morgan (Clementine)
- E17 Role ModelApr 12, 2005 · 44 min · ★ 7.8
Synopsis

House and his team battle to save a presidential hopeful, and House refuses to give in to Vogler's ultimatum when given the chance to save one of his team members.
Guest stars: Missy Crider (Susan), Chi McBride (Edward Vogler), Joe Morton (Gary Wright), Dominic Oliver (Reynolds), Elizabeth Karr (Hostess), Sahar Bibiyan (Clinic Nurse), Bobbin Bergstrom (Nurse)
- E18 Babies & BathwaterApr 19, 2005 · 44 min · ★ 8.1
Synopsis

House and his team battle to diagnose a pregnant patient's life-threatening illness, prompting her to make the most emotional decision of her life, and Vogler is determined to fire House.
Guest stars: Kenneth Choi (Dr. Lim), Chi McBride (Edward Vogler), Marin Hinkle (Naomi Randolph), Michael A. Goorjian (Sean Randolph), Michael Simpson (Joel Kaplan), Natalie Shaw (Rachel Kaplan), John Berg (Dr. Prather), Guy Camilleri (Hayden Brown)
- E19 KidsMay 3, 2005 · 44 min · ★ 7.7
Synopsis

House and his team race to diagnose a 12-year-old's illness - an illness with a shocking origin - and House asks Cameron to come back to her job.
Guest stars: Eddie McClintock (Coach Stahl), Ben Jelen (Dr. Roger Spain), Shari Headley (Dr. Arlene Marks), Erin Foster (Dr. Petra Gilmar), Skye McCole Bartusiak (Mary Carroll), Dylan Kussman (Mr. Carroll), Kelly Kirklyn (Mrs. Carroll), Diego Clare (Dawson)
- E20 Love HurtsMay 10, 2005 · 44 min · ★ 7.5
Synopsis

House and his team tackle the case of a young man with a penchant for odd behavior, and House prepares for his date with Cameron.
Guest stars: Christina Cox (Annette), Peter Graves (Myron), John Cho (Harvey Park), Elizabeth Sung (Marilyn Park), June Squibb (Ramona), Keone Young (Clyde Park), Matt Malloy (Aubrey Shifren), Kristoffer Ryan Winters (New Guy)
- E21 Three StoriesMay 17, 2005 · 44 min · ★ 9.0
Synopsis

House must decide whether to take the case of his ex-love's husband and he gives medical students a lecture they'll never forget.
Guest stars: Nicole Bilderback (Caring Student), Carmen Electra (Carmen Electra), Andrew Keegan (Rebellious Student), Josh Zuckerman (Keen Student), Brent Briscoe (Farmer), James Saxenmeyer (Late 30s Man / Golfer), Andi Eystad (Volleyball Player), Susan Gallagher (Volleyball Player's Mom)
- E22 HoneymoonMay 24, 2005 · 44 min · ★ 7.8
Synopsis

House is faced with a problem he may not be able to solve and Stacy returns.
Guest stars: Currie Graham (Mark Warner), Mark Hames (Ambulance Driver), Revital Krawetz (Woman), Sela Ward (Stacy Warner)
Cast & crew
Created by David Shore
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Reviews · from TMDB members
Ibraheem...Oct 29, 2017
I liked this show because House's character, but I was oblivious to most of their medical conversations. An advice: Don't watch it unless you understand a lot of medical terminology.
RobMay 10, 2023
Hugh Laurie brings the house down in this role. sorry, I just had to make that pun. If you want to be utterly entertained by a self-destructive Vicodin addict as he childishly plays God with the lives of his patients and root for him every step of the way as he does it, then this is the series for you.
gishkyDec 18, 2025
"This dying child needs more ratbites!" - Doctor House, probably - while popping another bottle of vicodin
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Hugh Laurie
Robert Sean Leonard
Omar Epps
Jesse Spencer
Odette Annable
Peter Jacobson
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